What We Do

Our Services

CGEn provides state-of-the-art genomics support to world-leading research projects addressing important biological questions. The three CGEn nodes combine their expertise to adopt and integrate new technologies, develop innovative protocols, create new databases, and pioneer new bioinformatics tools to decode whole genomes from humans and other species.

Our platform of sequencing instruments is accessible to Canadian and international researchers from all disciplines in academic, private, and government sectors for complete high-throughput, low-cost, and high-quality sequence generation and analysis services. CGEn also provides additional services supporting a wide range of genomic applications.

Our Expertise

CGEn builds on the combined knowledge and expertise of the three nodes in Toronto, Montreal and Vancouver.  These centres have an extensive track record in genomic science, leading, collaborating with and servicing the most important genomics programs in Canada from academic, private, and government sectors. Disciplines extend far beyond biomedical and health research, such as environment, infectious disease, agriculture, forestry, fisheries, zoology, botany, ecology, metagenomics, biofuels, bioremediation, disease surveillance, evolutionary biology, and others.

The CGEn team also has a strong track record in method and technology development generating some of the earliest publications for RNA sequencing Morin et al., 2008, and for analyzing histone modifications Robertson et al., 2007.

A number of bioinformatics tools developed by the CGEn centres have been adopted by researchers across the globe, examples include the CIRCOS viewer, which provides a graphical synopsis of genomic changes and alterations Krzywinski et al, 2009, and the ABySS assembler, which was the first short read assembler capable of assembling mammalian sized genomes Simpson et al, 2009.

Our Infrastructure

The CGEn platform, distributed across the three CGEn nodes, includes the most current sequencing technologies and analysis methodologies. In 2023, CGEn completed the installation of the Illumina NovaSeq X Plus and PacBio Revio sequencers. that enable increased throughput, faster and more affordable sequencing for short-read and long-read applications, respectively.

Our Technologies

Sequencing Technologies
  • Illunima Nova Seq X plus
  • Illumina NovaSeq 6000
  • Illumina NextSeq 500
  • Illumina MiSeq
  • PacBio Revio
  • PacBio Sequel IIe
  • Oxford Nanopore MinION
  • ABI 3730XL
Additional Technologies
  • 10X Genomics
  • Cytogenomics (FISH, karyotyping)
  • Real-time qPCR and digital droplet PCR
  • TaqMan and Short Tandem Repeat (STR) profiling
  • DNA Extraction robotics
  • Cell culture/immortalization facilities
  • Affymetrix Microarrays (GeneChip & GeneTitan)
  • Illumina Microarrays (HiScan & iScan)
  • Agena MassArray System